An educational intervention on attitudes in pharmacovigilance and adverse drug reactions reports among health-care professionals in a public hospital in the State of Mexico: An interventional and prospective assessment. Attitudes in pharmacovigilance
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sep 27, 2023
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https://doi.org/10.36677/medicinainvestigacion.v11i2.21124
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Mariana Ortiz Reynoso
http://orcid.org/0000-0002-1003-7881
Jesús Mata Maldonado
http://orcid.org/0000-0002-0967-8112
Sergio Alcalá-Alcalá Martha Díaz-Flores
http://orcid.org/0000-0001-7622-3153
Víctor Manuel Elizalde-Valdés
http://orcid.org/0000-0003-0899-7581
http://orcid.org/0000-0002-1003-7881
Jesús Mata Maldonado
http://orcid.org/0000-0002-0967-8112
Sergio Alcalá-Alcalá Martha Díaz-Flores
http://orcid.org/0000-0001-7622-3153
Víctor Manuel Elizalde-Valdés
http://orcid.org/0000-0003-0899-7581
Resumen
There are few studies on pharmacovigilance (PV) and adverse drug reactions (ADR) in Mexico. The aim was to assess the effect of a pharmacovigilance training program on attitudes among healthcare professionals in a public hospital in Mexico State. This study was conducted in 100 physicians and nurses. A questionnaire was designed to assess attitudes in PV; its reliability was determined with Cronbach's alpha coefficient and criterion validity with Delphi method and applied it. Based on the needs detected, a training program was designed, applied to healthcare professionals and yet again the questionnaire was applied. In addition, adverse drug reaction reports were reviewed and compared using Wilcoxon signed-rank test. A factor analysis was performed to identify the questionnaire’ main components. After the intervention, there were statistically significant differences; the number of monthly reports of suspected ADR significantly aroused, also improving the quality of the information collected. This study showed how an educational intervention helps increase positive abilities and attitudes about PV and ADR reports among healthcare professionals
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ORTIZ REYNOSO, Mariana et al.
An educational intervention on attitudes in pharmacovigilance and adverse drug reactions reports among health-care professionals in a public hospital in the State of Mexico: An interventional and prospective assessment..
Medicina e Investigación Universidad Autónoma del Estado de México, [S.l.], v. 11, n. 2, p. 41-46, sep. 2023.
ISSN 2594-0600.
Disponible en: <https://medicinainvestigacion.uaemex.mx/article/view/21124>. Fecha de acceso: 18 ago. 2026
doi: https://doi.org/10.36677/medicinainvestigacion.v11i2.21124.
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Esta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-SinObrasDerivadas 4.0.
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Datta, S., & Sengupta, S. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting in a tertiary care teaching hospital of Sikkim. Perspect Clin Res. 2015; 6 (4): 200. DOI: 10.4103/2229-3485.167096
Alshammari, T. M., Alamri, K. K., Ghawa, Y. A., Alohali, N. F., Abualkol, S. A., & Aljadhey, H. S. Knowledge and attitude of health-care professionals in hospitals towards pharmacovigilance in Saudi Arabia. Int J Clin Pharm. 2015; 37 6): 1104-1110. DOI: 10.1007/s11096-015-0165-5
Acuña-Ferradanes, A., González-Añón, D., Castillo-Páramo, A., Fornos-Pérez, J. A., Andrés-Iglesias, J. C., & Rodríguez, A. Metodología para evaluar las actitudes y aptitudes sobre farmacovigilancia en los farmacéuticos comunitarios. Aplicación en la provincia de Pontevedra. Pharm. care Esp. 2012: 110-121.
Diario Oficial de la Federación. “Instalación y operación de la Farmacovig-ilancia”. Norma Oficial Mexicana NOM-220-SSA1-2016. 19 July 2017. http://www.dof.gob.mx/nota_detalle.php?codigo=5490830&fecha=19/07/2017
Albadawi, T. E., Hassan, T. M., Eisa, N. O. A., Mohamed, E. Y., Abdalla, S. M., & Sami, W. Pharmacovigilance Knowledge and Attitude of Health Professionals: A Pre-and Post-intervention Study. J Res Med Dent Sc. 2019; 7 (5): 137-147.
Ganesan, S., Sandhiya, S., Reddy, K. C., Subrahmanyam, D. K., & Adithan, C. The impact of the educational intervention on knowledge, attitude, and practice of pharmacovigilance toward adverse drug reactions reporting among health-care professionals in a tertia-ry care hospital in South India. J Nat Sci Biol Med. 2017; 8 (2): 203. DOI: 10.4103/0976-9668.210014
Opadeyi, A. O., Fourrier-Réglat, A., & Isah, A. O. Educational intervention to improve the knowledge, attitude and practice of healthcare professionals regarding pharmacovigilance in South-South Nigeria. Ther Adv Drug Saf. 2019; 10: 2042098618816279. DOI: 10.1177/2042098618816279
AlKablani, T. S., AlShamsi, H. S., & Al-mutairi, A. G. Reporting on Adverse Drug Reactions: Knowledge, Atti-tudes and Practice Among Physicians Working at Healthcare Institutions in Al-Buraimi Governorate-Oman. Glo-bal Journal of Health Science. 2018; 10 (8): 107. DOI: 10.5539/gjhs.v10n8p107
Fang, H., Lin, X., Zhang, J., Hong, Z., Sugiyama, K., Nozaki, T., ... & Asa-kawa, T. Multifaceted interventions for improving spontaneous reporting of adverse drug reactions in a general hospital in China. BMC Pharmacol Toxicol. 2017; 18 (1): 1-9. DOI: 10.1186/s40360-017-0159-0