Adenopatia y tiroiditis subaguda posterior a la vacunación contra SARS-CoV-2 con CanSino
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sep 26, 2025
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https://doi.org/10.36677/medicinainvestigacion.v13i2.25430
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Monika Palacios Martínez
Rafael Bojalil Parra
http://orcid.org/0000-0002-5806-3675
http://orcid.org/0000-0002-5806-3675
Resumen
En los últimos años, el mundo ha atravesado un panorama poco alentador con la aparición de la pandemia de Sars-CoV-2. El desarrollo de vacunas con diferentes tecnologías ha permitido un mejor control del Covid-19. Las vacunas no están exentas de eventos adversos en el momento o después de su aplicación. Presentamos el caso de una mujer latina de 43 años que tras 12 días de aplicación de la nueva vacuna recombinante contra coronavirus (vector adenovirus tipo 5) CanSino, CanSino Biologics Inc. («CanSino BIO») (sse: 688185, hkex: 06185) desarrolló adenopatía axilar e infraclavicular; también desarrolló tiroiditis subaguda 4 meses después. Ambas patologías están relacionadas con procesos víricos y la respuesta inmunológica a los mismos. Hasta la fecha no existen reportes de la aparición de ambas afecciones en la misma paciente y no hay información de estos eventos adversos con la aplicación de la vacuna CanSino.
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PALACIOS MARTÍNEZ, Monika; BOJALIL PARRA, Rafael.
Adenopatia y tiroiditis subaguda posterior a la vacunación contra SARS-CoV-2 con CanSino.
Medicina e Investigación Universidad Autónoma del Estado de México, [S.l.], v. 13, n. 2, p. 127-132, sep. 2025.
ISSN 2594-0600.
Disponible en: <https://medicinainvestigacion.uaemex.mx/article/view/25430>. Fecha de acceso: 04 dic. 2025
doi: https://doi.org/10.36677/medicinainvestigacion.v13i2.25430.
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Esta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-SinObrasDerivadas 4.0.
Citas
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Mehta, N.; Marcus Sales, R.; Babagbemi K.; Levy, A,D.; McGrath, A.L.; Drotman M.; Dodelzon, K. Unilateral axillary Adenopathy in the setting of COVID-19 vaccine. Clin Imag 2021, 75,12–15. doi.org/10.1148/rycan.2021210038
Lam, D.L.; Flanagan M.R. Axillary Lymphadenopathy After COVID-19 Vaccination in a Woman With Breast Cancer. JAMA 2022, 327,175-176. doi: 10.1001/jama.2021.20010.
Iremli, B.G.; Sendur S.N.; Unluturk, U. Three cases of subacute thyroiditis following SARS-CoV-2 vaccine: post-vaccination ASIA syndrome. J Clin Endocrinol Metab 2021. doi: 10.1210/clinem/dgab373
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Chung, J.Y.; Thone M.N.; Kwon, Y.J. COVID‐19 vaccines: the status and perspectives in delivery points of view. Adv Drug Deliv Rev 2021, 170,1-25. doi:10.1016/J.ADDR.2020.12.011
De Giorgis, S.; Garlaschi, A.; Brunetti, N.; Tosto, S.; Rescinito, G.; Monetti, F.; Oddone, C.; Massa, B.; Pitto F.; Calabrese, M.; Tagliafico, A.S. Axillary adenopathy after COVID-19 vaccine in patients undergoing breast ultrasound. J Ultrason 2021, 21,e361–e364. doi: 10.15557/JoU.2021.0060.
Garreffa, E.; York, J.; Turnbull, A.; Kendrick, D. Regional lymphadenopathy following COVID-19 vaccination: considerations for primary care management. Br J Gen Pract 2021, 71,284-285. doi: 10.3399/bjgp21X716117.
Tu, W.; Gierada, D.S.; Joe, B.N. COVID-19 Vaccination–related Lymphadenopathy: What To Be Aware Of Radiology: Imag Can 2021, 3:e210038 •https://doi.org/10.1148/rycan.2021210038
Özütemiz C, D.A. Potter, A.Ö. Özütemiz et al. Lymphadenopathy after the third Covid-19 vaccine. Curr Prob Cancer Case Rep 2021, 4,100127 doi.org/10.1016/j.cpccr.2021.100127
Mortazavi, S. COVID-19 Vaccination-Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women. Am J Roentgenol 2021, 217,857-858. doi: 10.2214/AJR.21.25651.
Keshavarz, P.; Yazdanpanah, F.; Rafiee, F.; Mizandari, M. Lymphadenopathy Following COVID-19 Vaccination: Imaging Findings Review. Acad Radiol 2021, 28,1058-1071. doi: 10.1016/j.acra.2021.04.007.
Canan, A.; Kukkar, V. Unilateral lymphadenopathy after COVID-19 vaccination. Lung India 2021, 38,294. doi: 10.4103/lungindia.lungindia_91_21
Lehman, C.D.; D'Alessandro, H.A.; Mendoza, D.P.; Succi, M.D.; Kambadakone, A.; Lamb, L.R. Unilateral Lymphadenopathy After COVID-19 Vaccination: A Practical Management Plan for Radiologists Across Specialties. J Am Coll Radiol 2021, 18,843-852. doi: 10.1016/j.jacr.2021.03.001
Larkin, K.; Sharma, A.; Drachtman, R., Salaru, G. Supraclavicular lymphadenopathy after COVID-19 vaccination. Pediatr Blood Cancer 2021, 16:,e29516. doi: 10.1002/pbc.29516.
Franquemont, F.; Galvez, J. Subacute thyroiditis after mRNA vaccine for Covid-19. J Endocrine Soc 2021, 5,A956–7. doi: 10.1210/jendso/bvab048.1954
Oyibo, S. Subacute thyroiditis after receiving the adenovirusvectored vaccine for coronavirus disease Cureus 2021, 13:e16045. doi: 10.7759/cureus.16045
Desailloud, R.; Hober, D. Viruses and thyroiditis: an update. Virol J 2009, 6,5. doi: 10.1186/1743-422X-6-5